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FN ISI Export Format |
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VR 1.0 |
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PT J |
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AU Knobel, R |
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Holditch-Davis, D |
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AF Knobel, Robin |
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Holditch-Davis, Diane |
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TI Thermoregulation and heat loss prevention after birth and during |
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neonatal intensive-care unit stabilization of extremely low-birthweight |
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infants |
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SO JOGNN-JOURNAL OF OBSTETRIC GYNECOLOGIC AND NEONATAL NURSING |
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LA English |
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DT Article |
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DE delivery room resuscitation; ELBW infants; hypothermia; neonatal |
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thermoregulation |
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ID PREMATURE-INFANTS; MORTALITY; ASSOCIATION; SURVIVAL; DELIVERY; TRIAL; |
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LIFE |
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AB Extremely low-birthweight infants have inefficient thermoregulation due |
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to immaturity and may exhibit cold body temperatures after birth and |
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during their first 12 hours of life. Hypothermia in these infants can |
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lead to increased morbidity and mortality. Anecdotal notes made during |
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our recent study revealed extremely low-birthweight infants' |
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temperatures decreased with caregiver procedures such as umbilical line |
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insertion, intubations, obtaining chest x-rays, manipulating |
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intravenous lines, repositioning, suctioning, and taking vital signs |
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during the first 12 hours of life. Therefore, nursing interventions |
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should be undertaken to prevent heat loss during these caregiver |
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procedures. Nurses can improve the thermal environment for extremely |
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low-birthweight infants by prewarming the delivery room and placing the |
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infant in a plastic bag up to the neck during delivery room |
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stabilization to prevent heat loss. |
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C1 Univ N Carolina, Sch Nursing, Chapel Hill, NC USA. |
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Duke Univ, Sch Nursing, Durham, NC USA. |
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RP Knobel, R, 408 Long Point Rd, Chocowinity, NC 27817 USA. |
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EM rbknobel@earthlink.net |
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CR *AM AC PED AM HEAR, 2005, SUMM MAJOR CHANG GUI |
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*AM AC PED COLL OB, 1988, GID PER CAR |
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ANDERSON P, 1998, FETAL NEONATAL PHYSL, V1, P837 |
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ASKIN DF, 2002, JOGNN, V31, P318 |
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BARRETT E, 2003, MED PHYSL CELLULAR M, P1035 |
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CLOHERTY J, 2003, MANUAL NEONATAL CARE |
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KNOBEL RB, 2005, J PERINATOL, V25, P304 |
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KNOBEL RB, 2005, J PERINATOL, V25, P514 |
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LOUGHEAD MK, 1997, PEDIAT NURS, V23, P11 |
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NECHAD M, 1986, BROWN ADIPOSE TISSUE, P1 |
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SAUER P, 1995, THERMOREGULATION SIC, P9 |
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SEDIN G, 1995, THERMOREGULATION SIC, P21 |
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WIDMAIER J, 2005, VANDERS HUMAN PHYSL |
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NR 38 |
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TC 0 |
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PU BLACKWELL PUBLISHING |
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PI OXFORD |
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PA 9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND |
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SN 0884-2175 |
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J9 JOGNN |
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JI JOGNN |
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PD MAY-JUN |
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PY 2007 |
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VL 36 |
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IS 3 |
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BP 280 |
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EP 287 |
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PG 8 |
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SC Nursing; Obstetrics & Gynecology |
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GA 171YU |
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UT ISI:000246772100011 |
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ER |
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|
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PT J |
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AU Sandberg, KL |
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Poole, SD |
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Hamdan, A |
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Minton, PA |
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Sundell, HW |
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AF Sandberg, Kenneth L. |
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Poole, Stanley D. |
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Hamdan, Ashraf |
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Minton, Patricia A. |
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Sundell, Hakan W. |
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TI Prenatal nicotine exposure transiently alters the lung mechanical |
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response to hypoxia in young lambs |
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SO RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY |
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LA English |
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DT Article |
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DE respiratory physiology; respiratory function tests; nicotine; prenatal |
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exposure; tobacco smoke pollution; hypoxia; sheep |
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ID INFANT-DEATH-SYNDROME; VENTILATORY RESPONSES; CARDIORESPIRATORY |
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RESPONSE; PULMONARY-FUNCTION; CIGARETTE-SMOKING; MATERNAL SMOKING; |
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GENE-EXPRESSION; NEWBORN RAT; SURFACTANT; COTININE |
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AB To test the hypothesis that fetal nicotine exposure alters the lung |
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mechanical response to hypoxia (10% 02) 10 lambs were exposed during |
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the last fetal trimester to a low dose nicotine (LN) and 10 to a |
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moderate dose (MN) (maternal dose 0.5 and 1.5 mg/(kg day) free base, |
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respectively). There were 10 controls (C). At 12 days, minute |
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ventilation increased significantly less in NIN compared with LN but |
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not with C. In contrast to C and LN, MN did not show anticipated |
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increases in dynamic compliance, specific compliance and FRC or |
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decrease in lung resistance but had signs of airway hyperreactivity |
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during hypoxia. Nicotine exposure did not alter the cardiovascular |
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response. These adverse effects decreased with advancing age. In |
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summary, prenatal nicotine exposure alters the lung mechanical response |
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to hypoxia. We speculate that prenatal nicotine-induced alterations of |
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lung mechanics during hypoxia may contribute to an increased |
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vulnerability to hypoxic stress during infancy. (C) 2006 Elsevier B.V. |
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All rights reserved. |
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C1 Vanderbilt Univ, Sch Med, Dept Pediat, Nashville, TN 37232 USA. |
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Gothenburg Univ, Dept Women & Child Hlth, SE-41685 Gothenburg, Sweden. |
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RP Sundell, HW, Vanderbilt Univ, Sch Med, Dept Pediat, B-1220,MCN, |
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Nashville, TN 37232 USA. |
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EM hakan.sundell@vanderbilt.edu |
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CR ALTMAN DG, 1991, PRACTICAL STAT MED R, P431 |
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NR 55 |
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TC 0 |
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PU ELSEVIER SCIENCE BV |
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PI AMSTERDAM |
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PA PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS |
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SN 1569-9048 |
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J9 RESPIR PHYSIOL NEUROBIOL |
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JI Respir. Physiol. Neuro. |
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PD JUN 15 |
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PY 2007 |
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VL 156 |
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IS 3 |
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BP 283 |
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EP 292 |
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PG 10 |
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SC Physiology; Respiratory System |
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GA 161UH |
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UT ISI:000246041200006 |
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