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dpavlin |
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<!--Section Begins--><br> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>KLAVUXIL</i></b><b><sup>®</sup></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<i>suspension for intramammary(i/mam) administration</i> |
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</p> |
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<div align="justify"> |
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treatment of mastitis in lactating cows |
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<b><i>Composition</i></b><b></b> |
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Each injector with 3 g of suspension contains: |
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Amoxicillin as amoxicillin trihydrate 200.0 mg |
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dpavlin |
1.2 |
Clavulanic acid as potassium clavulanate 50.0 mg |
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dpavlin |
1.1 |
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</p> |
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</div> |
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Prednisolone 10.0 mg |
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dpavlin |
1.2 |
Adjuvants and carrier: potassium-sodium alumosilicate, cetylane, vaseline white |
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dpavlin |
1.1 |
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</p> |
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</div> |
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dpavlin |
1.2 |
and paraffin liquid up to 3.0 g |
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dpavlin |
1.1 |
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</p> |
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</div> |
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dpavlin |
1.2 |
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dpavlin |
1.1 |
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</p> |
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</div> |
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<b><i>Action</i></b> |
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</p> |
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</div> |
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Klavuxil<b><sup>®</sup></b> is a new approach to antibiotic treatment. Resistance of many bacteria is based on the action of beta-lactamase, which destroys penicillin molecule before it enters bacteria. Potassium clavulanate contained in Klavuxil<b><sup>®</sup></b> inactivates beta-lactamase. Actually, clavulanic acid interferes with bacterial immunity thus re-establishing their sensitivity to amoxicillin levels achieved in the mammary gland. |
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Klavuxil<b><sup>®</sup></b> oily suspension is particularly suitable for the treatment of mastitis in the lactating cows. It has broad antimicrobial and bactericidal effect on major causes of mastitis. Some pharmacodynamic properties of the active ingredients of i/mam suspension are: |
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- Amoxicillin is a semi-synthetic penicillin that inhibits networking of peptoglycan threads in the cell wall of the sensitive gram-positive and gram-negative bacteria. During bacterial growth it acts mostly bactericidally. |
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- Irrespective of its insignificant antibacterial effect, clavulanic acid effectively inhibits bacterial beta-lactamase, the enzymes frequently responsible for bacterial resistance to penicillins. |
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- Prednisolone has antiphlogistic effect and counteracts inflammation and edema, i. e. enables deeper penetration of amoxicillin. In the amount contained in Klavuxil<b><sup>®</sup></b> it does not diminish antimicrobial activity of the leukocytes in the udder. |
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</p> |
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The combination of active ingredients of the preparation is efficient against majority of the species causing mastitis: <i>Staphylococcus</i> spp. - including beta-lactamase producing strains; <i>Streptococcus</i> spp., i. e. <i>S. agalactiae</i>, <i>S. dysgalactiae</i> and <i>S. uberis</i>; <i>Actinomyces pyogenes</i> and some less important representatives of <i>Corynebacterium</i> and <i>E. coli </i>genera. In addition to these, Klavuxil<b><sup>®</sup></b> i/mam suspension has <i>in vitro</i> activity against the species that are infrequent causes of mastitis, e. g. <i>Bacillus cereus</i> and the species of <i>Bacteroides</i>, <i>Campylobacter</i>, <i>Klebsiella</i> and <i>Pasteurella </i>genera. |
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523 |
|
|
<div align="justify"> |
524 |
|
|
<p style="text-align: justify;"> |
525 |
|
|
|
526 |
|
|
<b><i>Indications</i></b><b></b> |
527 |
|
|
|
528 |
|
|
</p> |
529 |
|
|
</div> |
530 |
|
|
|
531 |
|
|
|
532 |
|
|
|
533 |
|
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|
534 |
|
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|
535 |
|
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|
536 |
|
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|
537 |
|
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|
538 |
|
|
|
539 |
|
|
|
540 |
|
|
|
541 |
|
|
|
542 |
|
|
<div align="justify"> |
543 |
|
|
<p style="text-align: justify;"> |
544 |
|
|
|
545 |
|
|
Treatment of mastitis in the lactating cows, particularly when the infections are due to the strains of <i>Staphylococcus </i>genera (including beta-lactamase producing strains) and <i>Streptococcus</i> <i>agalactiae</i>, <i>S. dysgalactiae</i>, <i>S. uberis</i> and <i>E. coli</i>. |
546 |
|
|
|
547 |
|
|
</p> |
548 |
|
|
</div> |
549 |
|
|
|
550 |
|
|
|
551 |
|
|
|
552 |
|
|
|
553 |
|
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|
554 |
|
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|
555 |
|
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|
556 |
|
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|
557 |
|
|
|
558 |
|
|
|
559 |
|
|
|
560 |
|
|
|
561 |
|
|
<div align="justify"> |
562 |
|
|
<p style="text-align: justify;"> |
563 |
|
|
|
564 |
|
|
|
565 |
|
|
|
566 |
|
|
</p> |
567 |
|
|
</div> |
568 |
|
|
|
569 |
|
|
|
570 |
|
|
|
571 |
|
|
|
572 |
|
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|
573 |
|
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|
574 |
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|
575 |
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|
576 |
|
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|
577 |
|
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|
578 |
|
|
|
579 |
|
|
|
580 |
|
|
<div align="justify"> |
581 |
|
|
<p style="text-align: justify;"> |
582 |
|
|
|
583 |
|
|
<b><i>Contraindications</i></b><b></b> |
584 |
|
|
|
585 |
|
|
</p> |
586 |
|
|
</div> |
587 |
|
|
|
588 |
|
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|
589 |
|
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|
590 |
|
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|
591 |
|
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592 |
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593 |
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594 |
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595 |
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|
596 |
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|
597 |
|
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|
598 |
|
|
|
599 |
|
|
<div align="justify"> |
600 |
|
|
<p style="text-align: justify;"> |
601 |
|
|
|
602 |
|
|
Do not administer to dry cows. |
603 |
|
|
|
604 |
|
|
</p> |
605 |
|
|
</div> |
606 |
|
|
|
607 |
|
|
|
608 |
|
|
|
609 |
|
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|
610 |
|
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|
611 |
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612 |
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|
613 |
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|
614 |
|
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|
615 |
|
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|
616 |
|
|
|
617 |
|
|
|
618 |
|
|
<div align="justify"> |
619 |
|
|
<p style="text-align: justify;"> |
620 |
|
|
|
621 |
|
|
|
622 |
|
|
|
623 |
|
|
</p> |
624 |
|
|
</div> |
625 |
|
|
|
626 |
|
|
|
627 |
|
|
|
628 |
|
|
|
629 |
|
|
|
630 |
|
|
|
631 |
|
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|
632 |
|
|
|
633 |
|
|
|
634 |
|
|
|
635 |
|
|
|
636 |
|
|
|
637 |
|
|
<div align="justify"> |
638 |
|
|
<p style="text-align: justify;"> |
639 |
|
|
|
640 |
|
|
Hypersensitivity to penicillins and cephalosporins, which is extremely rare. |
641 |
|
|
|
642 |
|
|
</p> |
643 |
|
|
</div> |
644 |
|
|
|
645 |
|
|
|
646 |
|
|
|
647 |
|
|
|
648 |
|
|
|
649 |
|
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|
650 |
|
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|
651 |
|
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|
652 |
|
|
|
653 |
|
|
|
654 |
|
|
|
655 |
|
|
|
656 |
|
|
<div align="justify"> |
657 |
|
|
<p style="text-align: justify;"> |
658 |
|
|
|
659 |
|
|
<b><i></i></b> |
660 |
|
|
|
661 |
|
|
</p> |
662 |
|
|
</div> |
663 |
|
|
|
664 |
|
|
|
665 |
|
|
|
666 |
|
|
|
667 |
|
|
|
668 |
|
|
|
669 |
|
|
|
670 |
|
|
|
671 |
|
|
|
672 |
|
|
|
673 |
|
|
|
674 |
|
|
|
675 |
|
|
<div align="justify"> |
676 |
|
|
<p style="text-align: justify;"> |
677 |
|
|
|
678 |
|
|
Administration and dosage |
679 |
|
|
|
680 |
|
|
</p> |
681 |
|
|
</div> |
682 |
|
|
|
683 |
|
|
|
684 |
|
|
|
685 |
|
|
|
686 |
|
|
|
687 |
|
|
|
688 |
|
|
|
689 |
|
|
|
690 |
|
|
|
691 |
|
|
|
692 |
|
|
|
693 |
|
|
|
694 |
|
|
<div align="justify"> |
695 |
|
|
<p style="text-align: justify;"> |
696 |
|
|
|
697 |
|
|
The drug is administered by i/mam route. Immediately prior to administration milk out the affected udder. Thoroughly clean and disinfect the teat ends and orifices. Introduce the injector into the beginning of the teat canal and slowly inject the contents. |
698 |
|
|
|
699 |
|
|
</p> |
700 |
|
|
</div> |
701 |
|
|
|
702 |
|
|
|
703 |
|
|
|
704 |
|
|
|
705 |
|
|
|
706 |
|
|
|
707 |
|
|
|
708 |
|
|
|
709 |
|
|
|
710 |
|
|
|
711 |
|
|
|
712 |
|
|
|
713 |
|
|
<div align="justify"> |
714 |
|
|
<p style="text-align: justify;"> |
715 |
|
|
|
716 |
|
|
|
717 |
|
|
|
718 |
|
|
</p> |
719 |
|
|
</div> |
720 |
|
|
|
721 |
|
|
|
722 |
|
|
|
723 |
|
|
|
724 |
|
|
|
725 |
|
|
|
726 |
|
|
|
727 |
|
|
|
728 |
|
|
|
729 |
|
|
|
730 |
|
|
|
731 |
|
|
|
732 |
|
|
<div align="justify"> |
733 |
|
|
<p style="text-align: justify;"> |
734 |
|
|
|
735 |
|
|
After application gently massage the udder upward, from the teat to the udder base to evenly distribute the drug in the gland cistern, milk ducts and alveoli. |
736 |
|
|
|
737 |
|
|
</p> |
738 |
|
|
</div> |
739 |
|
|
|
740 |
|
|
|
741 |
|
|
|
742 |
|
|
|
743 |
|
|
|
744 |
|
|
|
745 |
|
|
|
746 |
|
|
|
747 |
|
|
|
748 |
|
|
|
749 |
|
|
|
750 |
|
|
|
751 |
|
|
<div align="justify"> |
752 |
|
|
<p style="text-align: justify;"> |
753 |
|
|
|
754 |
|
|
|
755 |
|
|
|
756 |
|
|
</p> |
757 |
|
|
</div> |
758 |
|
|
|
759 |
|
|
|
760 |
|
|
|
761 |
|
|
|
762 |
|
|
|
763 |
|
|
|
764 |
|
|
|
765 |
|
|
|
766 |
|
|
|
767 |
|
|
|
768 |
|
|
|
769 |
|
|
|
770 |
|
|
<div align="justify"> |
771 |
|
|
<p style="text-align: justify;"> |
772 |
|
|
|
773 |
|
|
The content of one injector (3 g) is a single dose for each affected quarter. Klavuxil<b><sup>®</sup></b> is administered three times in 12-hour intervals. |
774 |
|
|
|
775 |
|
|
</p> |
776 |
|
|
</div> |
777 |
|
|
|
778 |
|
|
|
779 |
|
|
|
780 |
|
|
|
781 |
|
|
|
782 |
|
|
|
783 |
|
|
|
784 |
|
|
|
785 |
|
|
|
786 |
|
|
|
787 |
|
|
|
788 |
|
|
|
789 |
|
|
<div align="justify"> |
790 |
|
|
<p style="text-align: justify;"> |
791 |
|
|
|
792 |
|
|
|
793 |
|
|
|
794 |
|
|
</p> |
795 |
|
|
</div> |
796 |
|
|
|
797 |
|
|
|
798 |
|
|
|
799 |
|
|
|
800 |
|
|
|
801 |
|
|
|
802 |
|
|
|
803 |
|
|
|
804 |
|
|
|
805 |
|
|
|
806 |
|
|
|
807 |
|
|
|
808 |
|
|
<div align="justify"> |
809 |
|
|
<p style="text-align: justify;"> |
810 |
|
|
|
811 |
|
|
<b><i>Warnings and precautions</i></b><b></b> |
812 |
|
|
|
813 |
|
|
</p> |
814 |
|
|
</div> |
815 |
|
|
|
816 |
|
|
|
817 |
|
|
|
818 |
|
|
|
819 |
|
|
|
820 |
|
|
|
821 |
|
|
|
822 |
|
|
|
823 |
|
|
|
824 |
|
|
|
825 |
|
|
|
826 |
|
|
|
827 |
|
|
<div align="justify"> |
828 |
|
|
<p style="text-align: justify;"> |
829 |
|
|
|
830 |
|
|
Klavuxil<b><sup>®</sup></b> is ineffective against the infections caused by <i>Pseudomonas</i> spp. |
831 |
|
|
|
832 |
|
|
</p> |
833 |
|
|
</div> |
834 |
|
|
|
835 |
|
|
|
836 |
|
|
|
837 |
|
|
|
838 |
|
|
|
839 |
|
|
|
840 |
|
|
|
841 |
|
|
|
842 |
|
|
|
843 |
|
|
|
844 |
|
|
|
845 |
|
|
|
846 |
|
|
<div align="justify"> |
847 |
|
|
<p style="text-align: justify;"> |
848 |
|
|
|
849 |
|
|
|
850 |
|
|
|
851 |
|
|
</p> |
852 |
|
|
</div> |
853 |
|
|
|
854 |
|
|
|
855 |
|
|
|
856 |
|
|
|
857 |
|
|
|
858 |
|
|
|
859 |
|
|
|
860 |
|
|
|
861 |
|
|
|
862 |
|
|
|
863 |
|
|
|
864 |
|
|
|
865 |
|
|
<div align="justify"> |
866 |
|
|
<p style="text-align: justify;"> |
867 |
|
|
|
868 |
|
|
Persons hypersensitive to penicillins and/or cephalosporins should handle the preparation with care. After handling thoroughly wash the hands. |
869 |
|
|
|
870 |
|
|
</p> |
871 |
|
|
</div> |
872 |
|
|
|
873 |
|
|
|
874 |
|
|
|
875 |
|
|
|
876 |
|
|
|
877 |
|
|
|
878 |
|
|
|
879 |
|
|
|
880 |
|
|
|
881 |
|
|
|
882 |
|
|
|
883 |
|
|
|
884 |
|
|
<div align="justify"> |
885 |
|
|
<p style="text-align: justify;"> |
886 |
|
|
|
887 |
|
|
|
888 |
|
|
|
889 |
|
|
</p> |
890 |
|
|
</div> |
891 |
|
|
|
892 |
|
|
|
893 |
|
|
|
894 |
|
|
|
895 |
|
|
|
896 |
|
|
|
897 |
|
|
|
898 |
|
|
|
899 |
|
|
|
900 |
|
|
|
901 |
|
|
|
902 |
|
|
|
903 |
|
|
<div align="justify"> |
904 |
|
|
<p style="text-align: justify;"> |
905 |
|
|
|
906 |
|
|
<b><i>Withdrawal</i></b><b></b> |
907 |
|
|
|
908 |
|
|
</p> |
909 |
|
|
</div> |
910 |
|
|
|
911 |
|
|
|
912 |
|
|
|
913 |
|
|
|
914 |
|
|
|
915 |
|
|
|
916 |
|
|
|
917 |
|
|
|
918 |
|
|
|
919 |
|
|
|
920 |
|
|
|
921 |
|
|
|
922 |
|
|
<div align="left"> |
923 |
|
|
<p style="text-align: left;"> |
924 |
|
|
|
925 |
|
|
Meat, organs and other edible tissues 7 days |
926 |
|
|
|
927 |
|
|
</p> |
928 |
|
|
</div> |
929 |
|
|
|
930 |
|
|
|
931 |
|
|
|
932 |
|
|
|
933 |
|
|
|
934 |
|
|
|
935 |
|
|
|
936 |
|
|
|
937 |
|
|
|
938 |
|
|
|
939 |
|
|
|
940 |
|
|
|
941 |
|
|
<div align="left"> |
942 |
|
|
<p style="text-align: left;"> |
943 |
|
|
|
944 |
|
|
Milk 48 hours if milked 2-3 times daily |
945 |
|
|
|
946 |
|
|
</p> |
947 |
|
|
</div> |
948 |
|
|
|
949 |
|
|
|
950 |
|
|
|
951 |
|
|
|
952 |
|
|
|
953 |
|
|
|
954 |
|
|
|
955 |
|
|
|
956 |
|
|
|
957 |
|
|
|
958 |
|
|
|
959 |
|
|
|
960 |
|
|
<div align="justify"> |
961 |
|
|
<p style="text-align: justify;"> |
962 |
|
|
|
963 |
|
|
|
964 |
|
|
|
965 |
|
|
</p> |
966 |
|
|
</div> |
967 |
|
|
|
968 |
|
|
|
969 |
|
|
|
970 |
|
|
|
971 |
|
|
|
972 |
|
|
|
973 |
|
|
|
974 |
|
|
|
975 |
|
|
|
976 |
|
|
|
977 |
|
|
|
978 |
|
|
|
979 |
|
|
<div align="justify"> |
980 |
|
|
<p style="text-align: justify;"> |
981 |
|
|
|
982 |
|
|
<b><i>Storage</i></b> |
983 |
|
|
|
984 |
|
|
</p> |
985 |
|
|
</div> |
986 |
|
|
|
987 |
|
|
|
988 |
|
|
|
989 |
|
|
|
990 |
|
|
|
991 |
|
|
|
992 |
|
|
|
993 |
|
|
|
994 |
|
|
|
995 |
|
|
|
996 |
|
|
|
997 |
|
|
|
998 |
|
|
<div align="justify"> |
999 |
|
|
<p style="text-align: justify;"> |
1000 |
|
|
|
1001 |
|
|
Store in a dry and cool place (up to 15°C). Keep away from children. |
1002 |
|
|
|
1003 |
|
|
</p> |
1004 |
|
|
</div> |
1005 |
|
|
|
1006 |
|
|
|
1007 |
|
|
|
1008 |
|
|
|
1009 |
|
|
|
1010 |
|
|
|
1011 |
|
|
|
1012 |
|
|
|
1013 |
|
|
|
1014 |
|
|
|
1015 |
|
|
|
1016 |
|
|
|
1017 |
|
|
<div align="justify"> |
1018 |
|
|
<p style="text-align: justify;"> |
1019 |
|
|
|
1020 |
|
|
|
1021 |
|
|
|
1022 |
|
|
</p> |
1023 |
|
|
</div> |
1024 |
|
|
|
1025 |
|
|
|
1026 |
|
|
|
1027 |
|
|
|
1028 |
|
|
|
1029 |
|
|
|
1030 |
|
|
|
1031 |
|
|
|
1032 |
|
|
|
1033 |
|
|
|
1034 |
|
|
|
1035 |
|
|
|
1036 |
|
|
<div align="justify"> |
1037 |
|
|
<p style="text-align: justify;"> |
1038 |
|
|
|
1039 |
|
|
<b><i>Legal category</i></b><b></b> |
1040 |
|
|
|
1041 |
|
|
</p> |
1042 |
|
|
</div> |
1043 |
|
|
|
1044 |
|
|
|
1045 |
|
|
|
1046 |
|
|
|
1047 |
|
|
|
1048 |
|
|
|
1049 |
|
|
|
1050 |
|
|
|
1051 |
|
|
|
1052 |
|
|
|
1053 |
|
|
|
1054 |
|
|
|
1055 |
|
|
<div align="justify"> |
1056 |
|
|
<p style="text-align: justify;"> |
1057 |
|
|
|
1058 |
|
|
On prescription only. |
1059 |
|
|
|
1060 |
|
|
</p> |
1061 |
|
|
</div> |
1062 |
|
|
|
1063 |
|
|
|
1064 |
|
|
|
1065 |
|
|
|
1066 |
|
|
|
1067 |
|
|
|
1068 |
|
|
|
1069 |
|
|
|
1070 |
|
|
|
1071 |
|
|
|
1072 |
|
|
|
1073 |
|
|
|
1074 |
|
|
<div align="justify"> |
1075 |
|
|
<p style="text-align: justify;"> |
1076 |
|
|
|
1077 |
|
|
|
1078 |
|
|
|
1079 |
|
|
</p> |
1080 |
|
|
</div> |
1081 |
|
|
|
1082 |
|
|
|
1083 |
|
|
|
1084 |
|
|
|
1085 |
|
|
|
1086 |
|
|
|
1087 |
|
|
|
1088 |
|
|
|
1089 |
|
|
|
1090 |
|
|
|
1091 |
|
|
|
1092 |
|
|
|
1093 |
|
|
<div align="justify"> |
1094 |
|
|
<p style="text-align: justify;"> |
1095 |
|
|
|
1096 |
|
|
<b><i>Shelf life</i></b><b></b> |
1097 |
|
|
|
1098 |
|
|
</p> |
1099 |
|
|
</div> |
1100 |
|
|
|
1101 |
|
|
|
1102 |
|
|
|
1103 |
|
|
|
1104 |
|
|
|
1105 |
|
|
|
1106 |
|
|
|
1107 |
|
|
|
1108 |
|
|
|
1109 |
|
|
|
1110 |
|
|
|
1111 |
|
|
|
1112 |
|
|
<div align="justify"> |
1113 |
|
|
<p style="text-align: justify;"> |
1114 |
|
|
|
1115 |
|
|
Denoted on the packaging (18 months). |
1116 |
|
|
|
1117 |
|
|
</p> |
1118 |
|
|
</div> |
1119 |
|
|
|
1120 |
|
|
|
1121 |
|
|
|
1122 |
|
|
|
1123 |
|
|
|
1124 |
|
|
|
1125 |
|
|
|
1126 |
|
|
|
1127 |
|
|
|
1128 |
|
|
|
1129 |
|
|
|
1130 |
|
|
|
1131 |
|
|
<div align="justify"> |
1132 |
|
|
<p style="text-align: justify;"> |
1133 |
|
|
|
1134 |
|
|
|
1135 |
|
|
|
1136 |
|
|
</p> |
1137 |
|
|
</div> |
1138 |
|
|
|
1139 |
|
|
|
1140 |
|
|
|
1141 |
|
|
|
1142 |
|
|
|
1143 |
|
|
|
1144 |
|
|
|
1145 |
|
|
|
1146 |
|
|
|
1147 |
|
|
|
1148 |
|
|
|
1149 |
|
|
|
1150 |
|
|
<div align="justify"> |
1151 |
|
|
<p style="text-align: justify;"> |
1152 |
|
|
|
1153 |
|
|
<b><i>Supply</i></b><b></b> |
1154 |
|
|
|
1155 |
|
|
</p> |
1156 |
|
|
</div> |
1157 |
|
|
|
1158 |
|
|
|
1159 |
|
|
|
1160 |
|
|
|
1161 |
|
|
|
1162 |
|
|
|
1163 |
|
|
|
1164 |
|
|
|
1165 |
|
|
|
1166 |
|
|
|
1167 |
|
|
|
1168 |
|
|
|
1169 |
|
|
<div align="justify"> |
1170 |
|
|
<p style="text-align: justify;"> |
1171 |
|
|
|
1172 |
|
|
Box with 12 injectors with 3 g of suspension. |
1173 |
|
|
|
1174 |
|
|
</p> |
1175 |
|
|
</div> |
1176 |
|
|
|
1177 |
|
|
|
1178 |
|
|
|
1179 |
|
|
|
1180 |
|
|
|
1181 |
|
|
|
1182 |
|
|
|
1183 |
|
|
|
1184 |
|
|
|
1185 |
|
|
|
1186 |
|
|
|
1187 |
|
|
|
1188 |
|
|
<div align="justify"> |
1189 |
|
|
<p style="text-align: justify;"> |
1190 |
|
|
|
1191 |
|
|
<b></b> |
1192 |
|
|
|
1193 |
|
|
</p> |
1194 |
|
|
</div> |
1195 |
|
|
|
1196 |
|
|
|
1197 |
|
|
|
1198 |
|
|
|
1199 |
|
|
|
1200 |
|
|
|
1201 |
|
|
|
1202 |
|
|
|
1203 |
|
|
|
1204 |
|
|
|
1205 |
|
|
|
1206 |
|
|
|
1207 |
|
|
<div align="justify"> |
1208 |
|
|
<p style="text-align: justify;"> |
1209 |
|
|
|
1210 |
|
|
<b><i>Manufacturer</i></b><b></b> |
1211 |
|
|
|
1212 |
|
|
</p> |
1213 |
|
|
</div> |
1214 |
|
|
|
1215 |
|
|
|
1216 |
|
|
|
1217 |
|
|
|
1218 |
|
|
|
1219 |
|
|
|
1220 |
|
|
|
1221 |
|
|
|
1222 |
|
|
|
1223 |
|
|
|
1224 |
|
|
|
1225 |
|
|
|
1226 |
|
|
<div align="justify"> |
1227 |
|
|
<p style="text-align: justify;"> |
1228 |
|
|
|
1229 |
|
|
VETERINA Animal Health Ltd., Croatia |
1230 |
|
|
|
1231 |
|
|
</p> |
1232 |
|
|
</div> |
1233 |
|
|
|
1234 |
|
|
|
1235 |
|
|
|
1236 |
|
|
|
1237 |
|
|
|
1238 |
|
|
|
1239 |
|
|
|
1240 |
|
|
|
1241 |
|
|
|
1242 |
|
|
|
1243 |
|
|
|
1244 |
|
|
|
1245 |
|
|
<div align="justify"> |
1246 |
|
|
<p style="text-align: justify;"> |
1247 |
|
|
|
1248 |
|
|
|
1249 |
|
|
|
1250 |
|
|
</p> |
1251 |
|
|
</div> |
1252 |
|
|
|
1253 |
|
|
|
1254 |
|
|
|
1255 |
|
|
|
1256 |
|
|
|
1257 |
|
|
|
1258 |
|
|
|
1259 |
|
|
|
1260 |
|
|
|
1261 |
|
|
|
1262 |
|
|
|
1263 |
|
|
|
1264 |
|
|
<div align="left"> |
1265 |
|
|
<p style="text-align: left;"> |
1266 |
|
|
|
1267 |
|
|
|
1268 |
|
|
|
1269 |
|
|
</p> |
1270 |
|
|
</div> |
1271 |
|
|
|
1272 |
|
|
|
1273 |
|
|
|
1274 |
|
|
|
1275 |
|
|
|
1276 |
|
|
|
1277 |
|
|
|
1278 |
|
|
<!--Section Ends--> |
1279 |
|
|
|
1280 |
|
|
|
1281 |
|
|
|
1282 |
|
|
|
1283 |
|
|
|
1284 |
|
|
|
1285 |
|
|
|
1286 |
|
|
|