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<!--Section Begins--><br> |
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<div align="justify"> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b>PESTIKAL</b><b><sup>®</sup></b><b> LA SOTA SPF</b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<i>lyophilised vaccine against Newcastle disease La Sota strain for chicks, hens and turkey</i> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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<b><i>Composition</i></b><i></i> |
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</p> |
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</div> |
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The vaccine contains live lentogenic Newcastle disease virus, La Sota strain grown in the embryonated chicks' SPF eggs. One vaccinal dose contains at least 10<sup>6.0 </sup>EID<sub>50</sub> of this lentogenic virus. |
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</p> |
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</div> |
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<b><i>Action</i></b><b></b> |
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</p> |
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<p style="text-align: justify;"> |
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The vaccine stimulates formation of specific antibodies for Newcastle disease. |
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</p> |
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<b><i>Indications</i></b> |
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Immunisation of healthy fowl against Newcastle disease. |
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<b><i>Contraindications</i></b> |
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Unknown. |
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</p> |
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<b><i>Administration and dosage</i></b> |
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PESTIKAL<b><sup>®</sup></b> LA SOTA SPF vaccine may be administered by the following three routes: |
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<p style="text-align: justify;"> |
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<b><i>1. Oculonasally</i></b><b></b> |
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One dose of reconstituted vaccine is 0.1 mL, i. e. about two drops, irrespective of the age, or body weight of an animal. The vaccine is administered dropwise into the eye and nostril. |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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<b><i>2. In drinking water</i></b> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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Immediately before use, the vaccine should be reconstituted in cold and clean water without chlorine or other disinfectants, in the dosage equivalent to the number of birds to be vaccinated. |
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</p> |
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</div> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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Use 10 L of water to reconstitute 1000 vaccinal doses for the chicks in the first week of life, 20 L of water for the poultry aged 2-3 weeks and 40 L of water for two months old and older birds. |
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</p> |
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</div> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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To make the birds thirsty withhold normal supplies of water 3 hours prior to immunisation. Waterers should be clean, with no traces of food or disinfectant. Sufficient number of waterers should be provided, i. e. about 30% more than required for that age, to ensure that all birds take the water with the vaccine within one hour. |
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</p> |
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</div> |
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</p> |
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</div> |
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<p style="text-align: justify;"> |
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<b><i>3. Spraying</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Spraying ensures fast establishment of sound immunity and is, therefore, recommended when the flock is in the imminent risk of infection. Vaccination is performed with a sprayer forming 30-100 mm size particles. The particles for younger birds are larger than for the older. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Number of doses should correspond to the number of birds in a flock. Reconstitute 1000 doses of the vaccine in 100-150 mL of, preferably, distilled water. Prior to vaccination confine the birds to a smaller area and disconnect the ventilation. If the birds are in the cages or boxes, spray the vaccine directly over them. Over 4 days upon vaccination it is recommended to give the birds the drugs for prevention of bacterial and mycoplasmal infections, particularly if the vaccine is sprayed over the flock with the latent infection. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Immunity</i></b><b></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Immunity is developed on about day 5-6 post vaccination and is fully established after day 21. The younger the birds, the shorter duration of immunity. In the adult multiply vaccinated birds immunity is maintained over 3-5 months. |
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</p> |
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</div> |
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</p> |
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</div> |
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<b><i>Warnings and precautions</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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Vaccinate only healthy birds. |
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</p> |
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</div> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Once reconstituted use within 3 hours. |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Live vaccine against Newcastle disease very rarely causes conjunctivitis in humans. It is, therefore, recommended to wear a protective mask during spraying. |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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<b><i>Withdrawal</i></b> |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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Meat, organs and other edible tissues - 0 days. |
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</p> |
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</div> |
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<div align="justify"> |
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<p style="text-align: justify;"> |
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</p> |
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</div> |
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|
892 |
|
893 |
|
894 |
|
895 |
|
896 |
|
897 |
|
898 |
|
899 |
|
900 |
|
901 |
|
902 |
|
903 |
<div align="justify"> |
904 |
<p style="text-align: justify;"> |
905 |
|
906 |
<b><i>Storage</i></b> |
907 |
|
908 |
</p> |
909 |
</div> |
910 |
|
911 |
|
912 |
|
913 |
|
914 |
|
915 |
|
916 |
|
917 |
|
918 |
|
919 |
|
920 |
|
921 |
|
922 |
<div align="justify"> |
923 |
<p style="text-align: justify;"> |
924 |
|
925 |
Store in a dark place at 2-8°C (refrigerator). Keep away from children. |
926 |
|
927 |
</p> |
928 |
</div> |
929 |
|
930 |
|
931 |
|
932 |
|
933 |
|
934 |
|
935 |
|
936 |
|
937 |
|
938 |
|
939 |
|
940 |
|
941 |
<div align="justify"> |
942 |
<p style="text-align: justify;"> |
943 |
|
944 |
|
945 |
|
946 |
</p> |
947 |
</div> |
948 |
|
949 |
|
950 |
|
951 |
|
952 |
|
953 |
|
954 |
|
955 |
|
956 |
|
957 |
|
958 |
|
959 |
|
960 |
<div align="justify"> |
961 |
<p style="text-align: justify;"> |
962 |
|
963 |
<b><i>Shelf life</i></b> |
964 |
|
965 |
</p> |
966 |
</div> |
967 |
|
968 |
|
969 |
|
970 |
|
971 |
|
972 |
|
973 |
|
974 |
|
975 |
|
976 |
|
977 |
|
978 |
|
979 |
<div align="justify"> |
980 |
<p style="text-align: justify;"> |
981 |
|
982 |
Denoted on the packaging (2 years). |
983 |
|
984 |
</p> |
985 |
</div> |
986 |
|
987 |
|
988 |
|
989 |
|
990 |
|
991 |
|
992 |
|
993 |
|
994 |
|
995 |
|
996 |
|
997 |
|
998 |
<div align="justify"> |
999 |
<p style="text-align: justify;"> |
1000 |
|
1001 |
<b></b> |
1002 |
|
1003 |
</p> |
1004 |
</div> |
1005 |
|
1006 |
|
1007 |
|
1008 |
|
1009 |
|
1010 |
|
1011 |
|
1012 |
|
1013 |
|
1014 |
|
1015 |
|
1016 |
|
1017 |
<div align="justify"> |
1018 |
<p style="text-align: justify;"> |
1019 |
|
1020 |
<b><i>Legal category</i></b><b></b> |
1021 |
|
1022 |
</p> |
1023 |
</div> |
1024 |
|
1025 |
|
1026 |
|
1027 |
|
1028 |
|
1029 |
|
1030 |
|
1031 |
|
1032 |
|
1033 |
|
1034 |
|
1035 |
|
1036 |
<div align="justify"> |
1037 |
<p style="text-align: justify;"> |
1038 |
|
1039 |
On prescription only. |
1040 |
|
1041 |
</p> |
1042 |
</div> |
1043 |
|
1044 |
|
1045 |
|
1046 |
|
1047 |
|
1048 |
|
1049 |
|
1050 |
|
1051 |
|
1052 |
|
1053 |
|
1054 |
|
1055 |
<div align="justify"> |
1056 |
<p style="text-align: justify;"> |
1057 |
|
1058 |
<b></b> |
1059 |
|
1060 |
</p> |
1061 |
</div> |
1062 |
|
1063 |
|
1064 |
|
1065 |
|
1066 |
|
1067 |
|
1068 |
|
1069 |
|
1070 |
|
1071 |
|
1072 |
|
1073 |
|
1074 |
<div align="justify"> |
1075 |
<p style="text-align: justify;"> |
1076 |
|
1077 |
<b><i>Supply</i></b> |
1078 |
|
1079 |
</p> |
1080 |
</div> |
1081 |
|
1082 |
|
1083 |
|
1084 |
|
1085 |
|
1086 |
|
1087 |
|
1088 |
|
1089 |
|
1090 |
|
1091 |
|
1092 |
|
1093 |
<div align="justify"> |
1094 |
<p style="text-align: justify;"> |
1095 |
|
1096 |
Box with bottles of 25, 10x1000 and 10x2000 doses. |
1097 |
|
1098 |
</p> |
1099 |
</div> |
1100 |
|
1101 |
|
1102 |
|
1103 |
|
1104 |
|
1105 |
|
1106 |
|
1107 |
|
1108 |
|
1109 |
|
1110 |
|
1111 |
|
1112 |
<div align="justify"> |
1113 |
<p style="text-align: justify;"> |
1114 |
|
1115 |
|
1116 |
|
1117 |
</p> |
1118 |
</div> |
1119 |
|
1120 |
|
1121 |
|
1122 |
|
1123 |
|
1124 |
|
1125 |
|
1126 |
|
1127 |
|
1128 |
|
1129 |
|
1130 |
|
1131 |
<div align="justify"> |
1132 |
<p style="text-align: justify;"> |
1133 |
|
1134 |
<b><i>Manufacturer</i></b><b></b> |
1135 |
|
1136 |
</p> |
1137 |
</div> |
1138 |
|
1139 |
|
1140 |
|
1141 |
|
1142 |
|
1143 |
|
1144 |
|
1145 |
|
1146 |
|
1147 |
|
1148 |
|
1149 |
|
1150 |
<div align="justify"> |
1151 |
<p style="text-align: justify;"> |
1152 |
|
1153 |
VETERINA Animal Health Ltd., Croatia<b></b> |
1154 |
|
1155 |
</p> |
1156 |
</div> |
1157 |
|
1158 |
|
1159 |
|
1160 |
|
1161 |
|
1162 |
|
1163 |
|
1164 |
|
1165 |
|
1166 |
|
1167 |
|
1168 |
|
1169 |
<div align="justify"> |
1170 |
<p style="text-align: justify;"> |
1171 |
|
1172 |
|
1173 |
|
1174 |
</p> |
1175 |
</div> |
1176 |
|
1177 |
|
1178 |
|
1179 |
|
1180 |
|
1181 |
|
1182 |
|
1183 |
|
1184 |
|
1185 |
|
1186 |
|
1187 |
|
1188 |
<div align="justify"> |
1189 |
<p style="text-align: justify;"> |
1190 |
|
1191 |
<b><i>Important note</i></b> |
1192 |
|
1193 |
</p> |
1194 |
</div> |
1195 |
|
1196 |
|
1197 |
|
1198 |
|
1199 |
|
1200 |
|
1201 |
|
1202 |
|
1203 |
|
1204 |
|
1205 |
|
1206 |
|
1207 |
<div align="justify"> |
1208 |
<p style="text-align: justify;"> |
1209 |
|
1210 |
In every animal population there are some with poorer response to vaccination. In addition to proper storage and administration, success of vaccination depends on hereditary factors, age of the animal, subclinical diseases, maternal antibodies, feeding, stress and concurrent administration of other medicines. |
1211 |
|
1212 |
</p> |
1213 |
</div> |
1214 |
|
1215 |
|
1216 |
|
1217 |
|
1218 |
|
1219 |
|
1220 |
|
1221 |
|
1222 |
|
1223 |
|
1224 |
|
1225 |
|
1226 |
<div align="justify"> |
1227 |
<p style="text-align: justify;"> |
1228 |
|
1229 |
|
1230 |
|
1231 |
</p> |
1232 |
</div> |
1233 |
|
1234 |
|
1235 |
|
1236 |
|
1237 |
|
1238 |
|
1239 |
|
1240 |
|
1241 |
|
1242 |
|
1243 |
|
1244 |
|
1245 |
<div align="justify"> |
1246 |
<p style="text-align: justify;"> |
1247 |
|
1248 |
Given the variations in vaccination programmes, before vaccinating the whole flock it is recommended to consult the veterinarian - a poultry expert.<b></b> |
1249 |
|
1250 |
</p> |
1251 |
</div> |
1252 |
|
1253 |
|
1254 |
|
1255 |
|
1256 |
|
1257 |
|
1258 |
|
1259 |
|
1260 |
|
1261 |
|
1262 |
|
1263 |
|
1264 |
<div align="justify"> |
1265 |
<p style="text-align: justify;"> |
1266 |
|
1267 |
|
1268 |
|
1269 |
</p> |
1270 |
</div> |
1271 |
|
1272 |
|
1273 |
|
1274 |
|
1275 |
|
1276 |
|
1277 |
|
1278 |
|
1279 |
|
1280 |
|
1281 |
|
1282 |
|
1283 |
<div align="left"> |
1284 |
<p style="text-align: left;"> |
1285 |
|
1286 |
|
1287 |
|
1288 |
</p> |
1289 |
</div> |
1290 |
|
1291 |
|
1292 |
|
1293 |
|
1294 |
|
1295 |
|
1296 |
|
1297 |
<!--Section Ends--> |
1298 |
|
1299 |
|
1300 |
|
1301 |
|
1302 |
|
1303 |
|
1304 |
|
1305 |
|